In an effort to spotlight recent research progress, cureCADASIL facilitated the CADASIL Connection series of webinars. These insightful, pre-recorded sessions offer invaluable opportunities to educate and unite a diverse audience of researchers, clinicians, and patients.
We invite you to take advantage of these valuable resources to deepen your understanding of CADASIL and stay informed about its evolving landscape. Input your name and email address to gain access to the recordings via the links below.
Watch Our Webinars
cureCADASIL Webinar Registration – June 2025
Dr. Helena Karlström
Immunization Therapies for CADASIL
Helena Karlström has made important contributions to understanding the mechanisms in Notch3 biology, in relation to the familial small vessel disease CADASIL. Her lab aims to better understand the molecular mechanisms of this condition to develop therapeutics to tackle CADASIL.
The hypothesis is that if the immune system can be harnessed to clear the Notch3 deposits, CADASIL can potentially be halted, and the progression reversed. The lab has recently developed an active immunotherapy project with encouraging results. Ongoing studies aim to develop biomarkers to assess disease progression and to generate monoclonal antibodies that target Notch3 aggregates for use as a passive immunization therapy.
CADASIL Connection Webinar Registration – April 2024
Fanny Elahi, M.D., Ph.D.
The Power of Patient-Partnered Research in CADASIL
The Chan Zuckerberg Initiative-funded Patient-Partnered Collaboration between cureCADASIL and Dr. Elahi’s team has resulted in significant advancements in CADASIL research. By collaborating with patients, Dr. Elahi has gained novel insights into the disease and the patient experience. She will share advancements made in collaboration with patients and patient advocates.
CADASIL Connection Webinar Registration – March 2024
Elisa Ferrante Ph.D.
CADASIL Clinical Studies at the National Institutes of Health
CADASIL Connection Webinar Registration – January 2024
Family Participation: The Key to Success in Genetic Research
CADASIL Connection Webinar Registration – October 2023
Single-Cell RNA Sequencing for Discovering Therapeutic Drug Targets in CADASIL
CADASIL Connection Webinar Recording – May 2023
CADASIL vessel-on-chip for disease modeling and drug development
Marc Vila Cuenca, PhD, a senior post-doctoral researcher in the Orlova Lab and CADASIL research group at the Leiden University Medical Center in the Netherlands, discusses vessel-on-chip as an emerging technology to understand the structure and function of blood vessels in the CADASIL disease and to study potential therapies.
CADASIL Connection Webinar Recording – November 2022
The CADASIL Patient-Partnered Therapeutic Discovery Pipeline
CADASIL Connection Webinar Recording – July 2022
Learn about the New $12M NIH-Funded CADASIL Consortium Study
CADASIL Connection Webinar Recording – April 2022
Masayo Koide, MD, PhD
Capillary dysfunction by CADASIL: The smallest vessels have the biggest impact
Dr. Mayaso Koide, PhD, from the Department of Pharmacology, University of Vermont, and recipient of a University of Pennsylvania Orphan Disease Center Million Dollar Bike Ride research grant, presents her research on the impact of CADASIL on brain capillaries and their regulation of cerebral blood flow.
CADASIL Connection Webinar Recording – December 2021
Dr. Julie Rutten, MD, PhD from the Department of Clinical Genetics of the Leiden University Medical Center (LUMC), The Netherlands presents her research on NOTCH3 genetic mutations and their relationship to the clinical presentation of CADASIL.
CADASIL Connection Webinar Recording – April 2021
Fabrice Dabertrand, PhD Associate Professor of Anesthesiology and Pharmacology at University of Colorado, Anschutz Medical Campus and recipient of the 2019 Million Dollar Bike Ride (MDBR) seed grant (made possible by donations from the CADASIL community in partnership with cureCADASIL and Penn Medicine Orphan Disease Center) shares insights on cerebral blood flow in a CADASIL mouse model, explains what pericytes are and their role as well as the effects of PIP₂ in increasing blood flow to the brain.
CADASIL Connection Webinar Recording – September 2018
CADASIL Connection Webinar Recording – April 2018
Dr. Wang is Chief of Neurology at the VA Ann Arbor Healthcare System and Professor of Neurology at the University of Michigan where his lab studies the mechanisms of vascular degeneration and defining pathological proteins that build up in CADASIL and here he will share this exciting work in advancing our understanding of CADASIL.
CADASIL Connection Webinar Recording – February 2018
CADASIL Connection Webinar Recording – December 2017
CADASIL Connection Webinar Recording – October 2017
Dr. Manfred Boehm, Senior Investigator Laboratory of Cardiovascular Regenerative Medicine at the National Heart, Lung, and Blood Institute (NHLBI) and Principal Investigator for the CADASIL Disease Discovery Clinical Trial shares an inside view of the CADASIL Disease Discovery Study being conducted at the National Institute of Health.
CADASIL Connection Webinar Recording – August 2017
What’s Next?
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This cureCADASIL webinar series is supported by a grant from Global Genes, generous community donations and time of valued volunteers.
