Uniting patients, researchers, and clinicians to find a cure for CADASIL

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Share Your Story

We want to hear from you! Share your CADASIL journey and its impact on your daily life or that of your family member. From symptoms to diagnosis and doctor visits, take us on your path.  What advice can you offer to empower others as they navigate their own journeys?

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What is CADASIL?

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is a rare, inherited form of cerebrovascular disease that occurs when the thickening of small blood vessel walls in the brain’s white matter blocks the flow of blood to the brain. It is the most common hereditary condition leading to small-vessel vascular cognitive impairment and dementia.

CADASIL Testing

A genetic blood test is considered the gold standard for diagnosing CADASIL. Testing indicated when clinical findings (migraines with early-onset strokes and dementia), MRI findings, and family history raise a high index of suspicion.

Doctor Directory

Finding the right healthcare provider can be a challenge when you have a rare disease like CADASIL. Since 2012, we have been reaching out, educating doctors about CADASIL. This year we are putting CADASIL information into the hands of providers to support the families they serve.

CADASIL Support

cureCADASIL hosts several local meet ups and encourages others to reach out to CADASIL families near you. This local networking can be a source of support for you as well as a springboard for local advocacy for CADASIL.

What is CADASIL?

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is a rare, inherited form of cerebrovascular disease that occurs when the thickening of small blood vessel walls in the brain’s white matter blocks the flow of blood to the brain. It is the most common hereditary condition leading to small-vessel vascular cognitive impairment and dementia.

CADASIL Testing

A genetic blood test is considered the gold standard for diagnosing CADASIL. Testing indicated when clinical findings (migraines with early-onset strokes and dementia), MRI findings, and family history raise a high index of suspicion.

Doctor Directory

Finding the right healthcare provider can be a challenge when you have a rare disease like CADASIL. Since 2012, we have been reaching out, educating doctors about CADASIL. This year we are putting CADASIL information into the hands of providers to support the families they serve.

CADASIL Support

cureCADASIL hosts several local meet ups and encourages others to reach out to CADASIL families near you. This local networking can be a source of support for you as well as a springboard for local advocacy for CADASIL.

News, Events, and UpdatesNews, Events, and Updates

For the Patient

2025 PIM Meeting Update

July 16, 2025|

A heartfelt thank you to all who joined us virtually and in person for the 2025 cureCADASIL Patient-Investigator Meeting. From powerful patient stories to exciting progress from leading CADASIL researchers, the meeting was [...]

Scientific Advisory Board Meeting Update

July 16, 2025|

Our cureCADASIL Scientific Advisory Board met on June 6, welcoming several newly appointed members from the scientific community. The meeting sparked valuable discussions and fresh perspectives that will carry forward into our fall [...]

Thank You for Supporting Team CADASIL in the MDBR

July 16, 2025|

On June 14, 2025, cureCADASIL proudly participated in the 12th Annual Million Dollar Bike Ride—and thanks to your incredible support, we met our fundraising goal! Every dollar raised will go directly toward advancing [...]