Uniting patients, researchers, and clinicians to find a cure for CADASIL

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Share Your Story

We want to hear from you! Share your CADASIL journey and its impact on your daily life or that of your family member. From symptoms to diagnosis and doctor visits, take us on your path.  What advice can you offer to empower others as they navigate their own journeys?

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What is CADASIL?

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is a rare, inherited form of cerebrovascular disease that occurs when the thickening of small blood vessel walls in the brain’s white matter blocks the flow of blood to the brain. It is the most common hereditary condition leading to small-vessel vascular cognitive impairment and dementia.

CADASIL Testing

A genetic blood test is considered the gold standard for diagnosing CADASIL. Testing indicated when clinical findings (migraines with early-onset strokes and dementia), MRI findings, and family history raise a high index of suspicion.

Doctor Directory

Finding the right healthcare provider can be a challenge when you have a rare disease like CADASIL. Since 2012, we have been reaching out, educating doctors about CADASIL. This year we are putting CADASIL information into the hands of providers to support the families they serve.

CADASIL Support

cureCADASIL hosts several local meet ups and encourages others to reach out to CADASIL families near you. This local networking can be a source of support for you as well as a springboard for local advocacy for CADASIL.

What is CADASIL?

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is a rare, inherited form of cerebrovascular disease that occurs when the thickening of small blood vessel walls in the brain’s white matter blocks the flow of blood to the brain. It is the most common hereditary condition leading to small-vessel vascular cognitive impairment and dementia.

CADASIL Testing

A genetic blood test is considered the gold standard for diagnosing CADASIL. Testing indicated when clinical findings (migraines with early-onset strokes and dementia), MRI findings, and family history raise a high index of suspicion.

Doctor Directory

Finding the right healthcare provider can be a challenge when you have a rare disease like CADASIL. Since 2012, we have been reaching out, educating doctors about CADASIL. This year we are putting CADASIL information into the hands of providers to support the families they serve.

CADASIL Support

cureCADASIL hosts several local meet ups and encourages others to reach out to CADASIL families near you. This local networking can be a source of support for you as well as a springboard for local advocacy for CADASIL.

News, Events, and UpdatesNews, Events, and Updates

For the Patient

June 28th is the Patient-Investigator Meeting

June 19, 2025|

Each year, we close our Patient-Investigator Meeting with a Q&A panel discussion that brings together patients, families, and researchers. This session is always a highlight of the meeting, offering an opportunity for open [...]

CADASIL Consortium June Webinar

June 19, 2025|

Upcoming Webinar: CADASIL Consortium – An Update (2025)We are pleased to invite you to an important upcoming webinar hosted by the CADASIL Consortium on: 🗓️ Monday, June 30, 2025🕒 4PM PT | 5PM [...]

cureCADASIL Webinar – LIVE Recording

June 12, 2025|

Missed our recent CureCADASIL webinar on “Immunization Therapies for CADASIL”? The full recording is now available! Hear from Helena Karlström of the Karolinska Institute as she discusses promising advances in CADASIL immunotherapy. Hosted [...]