Join the CADASIL Community Natural History Study  —  Your participation helps facilitate CADASIL research and paves the way for therapeutic clinical trials.  Join Today → CADASIL Community Natural History Study  —  Your participation helps facilitate CADASIL research and paves the way for therapeutic clinical trials.  Join Today → CADASIL Community Natural History Study  —  Your participation helps facilitate CADASIL research and paves the way for therapeutic clinical trials.  Join Today →
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Rare Disease Research & Advocacy

Uniting patients, researchers, and clinicians to find a cure for CADASIL

cureCADASIL is a volunteer-led nonprofit advancing research, awareness, and support for those living with CADASIL — a rare genetic disorder affecting the brain's small blood vessels.

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0Years of Advocacy
0Research Grants Funded
0Million Dollar Bike Ride
100%Volunteer Led Organization

Join the CADASIL Community Natural History Study

The patient registry is one of the most important tools we have to accelerate research. By joining, you help researchers understand CADASIL better, and you may be matched with clinical studies that need participants like you.

Join the Registry

Where would you like to start?

Find what you need

Newly Diagnosed
I or someone I love has CADASIL
Learn about the disease, find a specialist, connect with others, and access patient support resources.
Get started
Supporters & Donors
I want to support CADASIL research
Donate, fundraise, or participate in the Million Dollar Bike Ride to fund groundbreaking research.
Support the cause
Researchers & Clinicians
I work in medicine or research
Explore active studies, apply for research grants, and connect with the CADASIL research community.
Explore research

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As a volunteer-led nonprofit, every dollar you give goes directly toward advancing research and supporting patients

CADASIL is a rare genetic condition affecting the brain's small blood vessels, leading to strokes, migraines, and dementia. cureCADASIL funds the research that brings us closer to treatments and a cure.

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Research We Support

All research
Active Study

CADASIL Consortium Natural History Study

A multi-site study tracking CADASIL progression to inform future clinical trials and treatment development.

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CZI-Funded

Chan Zuckerberg Initiative CADASIL Study

Patient-partnered collaboration led by Dr. Fanny Elahi at Icahn School of Medicine at Mount Sinai.

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Active Study

CADASIL Community Natural History Study

Join the registry to help researchers understand CADASIL better and match patients with clinical studies.

Join today
NIH Study

NIH/NHLBI CADASIL Natural History Study

Led by Elisa Ferrante, PhD at the NIH — seeking CADASIL patients to participate in groundbreaking research.

Participate