Uniting patients, researchers, and clinicians to find a cure for CADASIL

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fall fundraiser 2024

Let’s Fill the Jar!

We need your help to advance research, develop treatments, and improve the lives of individuals affected by CADASIL. Your support is crucial in bringing hope and progress to those living with CADASIL.

Through our involvement in the University of Pennsylvania Orphan Disease Center’s Million Dollar Bike Ride, we annually contribute essential “seed money” for CADASIL research. However, there is more work to be done.

Beyond backing existing studies in the US, we are initiating a new natural history study of our own to enhance our readiness for future therapeutic clinical trials.

We’ve raised $4,500 to date, but our goal is $20,000 – can you help us fill the jar?

join the movement

Share Your Story

We want to hear from you! Share your CADASIL journey and its impact on your daily life or that of your family member. From symptoms to diagnosis and doctor visits, take us on your path.  What advice can you offer to empower others as they navigate their own journeys?

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What is CADASIL?

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is a rare, inherited form of cerebrovascular disease that occurs when the thickening of small blood vessel walls in the brain’s white matter blocks the flow of blood to the brain. It is the most common hereditary condition leading to small-vessel vascular cognitive impairment and dementia.

CADASIL Testing

A genetic blood test is considered the gold standard for diagnosing CADASIL. Testing indicated when clinical findings (migraines with early-onset strokes and dementia), MRI findings, and family history raise a high index of suspicion.

Doctor Directory

Finding the right healthcare provider can be a challenge when you have a rare disease like CADASIL. Since 2012, we have been reaching out, educating doctors about CADASIL. This year we are putting CADASIL information into the hands of providers to support the families they serve.

CADASIL Support

cureCADASIL hosts several local meet ups and encourages others to reach out to CADASIL families near you. This local networking can be a source of support for you as well as a springboard for local advocacy for CADASIL.

What is CADASIL?

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy) is a rare, inherited form of cerebrovascular disease that occurs when the thickening of small blood vessel walls in the brain’s white matter blocks the flow of blood to the brain. It is the most common hereditary condition leading to small-vessel vascular cognitive impairment and dementia.

CADASIL Testing

A genetic blood test is considered the gold standard for diagnosing CADASIL. Testing indicated when clinical findings (migraines with early-onset strokes and dementia), MRI findings, and family history raise a high index of suspicion.

Doctor Directory

Finding the right healthcare provider can be a challenge when you have a rare disease like CADASIL. Since 2012, we have been reaching out, educating doctors about CADASIL. This year we are putting CADASIL information into the hands of providers to support the families they serve.

CADASIL Support

cureCADASIL hosts several local meet ups and encourages others to reach out to CADASIL families near you. This local networking can be a source of support for you as well as a springboard for local advocacy for CADASIL.

News, Events, and UpdatesNews, Events, and Updates

For the Patient

CADASIL Consortium December Webinar

December 1, 2024|

Please join the CADASIL Consortium on Monday, December 9th, 5pm PT / 7pm CT / 8pm ET for their upcoming webinar on family planning and IVF for individuals with CADASIL. Dr. Melissa Russo, [...]

CADASIL Consortium November Webinar

November 7, 2024|

Please join the CADASIL Consortium on Wednesday, November 20 at 3pm PT/5pm CT/6pm ET. Laura Eisenmenger, MD, will lead the webinar entitled MRI in CADASIL: What are We Imaging and Why? Dr. Eisenmenger [...]

Fall Fundraising Campaign

October 11, 2024|

Fall Fundraiser 2024 Fill the Jar Campaign We need your help to advance research, develop treatments, and improve the lives of individuals affected by CADASIL. Your support is crucial in bringing [...]