CZI Patient-Partnered Collaboration Study

Lead Investigator: Dr. Fanny Elahi, MD, PhD, Icahn School of Medicine at Mount Sinai

Research Contact: Ruth Axton, [email protected]

Dr. Fanny Elahi, MD, PhD at the Icahn School of Medicine at Mount Sinai is leading a multi-disciplinary team to use blood donated by participants to: (1) characterize your immune system; (2) test the connection between any immune system differences detected with clinical symptoms; (3) identify molecular biomarkers (such as proteins) that can track disease progression; and (4) leverage obtained molecular signatures in blood to build biological models of blood vessels in a dish. All these will build the critical foundation to reach the ultimate goal of screening drugs for discovery of treatments for CADASIL, to slow progression of symptoms and eventually prevent onset of disease.

Patient Participation
We need blood samples and other standard assessments (brief medical exam, brain imaging, and memory tests) from individuals living with CADASIL and from healthy volunteers (family members, friends).

For more information and to join the study, please contact Ruth Axton ([email protected]).