The Past, Present, and Future come together at cureCADASIL Patient Investigator Meeting 2026

Thank you to our presenters, attendees, and Board for another strong PIM. The presentations made clear that research efforts are becoming more aligned, that momentum is building across the community, and that patient participation remains central to continuing this progress in research.

We’ll be updating this page with recordings and presentation materials so you can go back to the full conversations and hear directly from the speakers and attendees. There’s value in taking the time to listen through how this work is evolving and where the needs are now and how you can help further this work.

If you have any questions, please contact us at info@curecadasil.org

Schedule of Events

Time Event
9:00-9:10 am Welcome-Bert Kasiske, cureCADASIL 2026 President
9:10-9:40 am Chan Zuckerberg Initiative Results & Future Directions presented by Lighwa Ncube Clinical Research Manager & Nikolas Karvelas Postdoctoral Fellow, Elahi Lab Icahn School of Medicine at Mt. Sinai
9:40-10:10am Immunization Therapies for CADASIL presented by Helena Karlström Associate Professor & Senior Lecturer at Karolinska Instituet-2024 MDBR Recipient
10:10-10:40am Small Molecule, Big Hopes for CADASIL Therapy Targeting RUNX1 presented by Joe Arbolea-Velasquez MD, PhD Associate Scientist Schepens Eye Research Institute Harvard Medical School
10:40-11:10am NIH Program Update presented by Manfred Boehm, MD Senior Investigator NIH Senior Investigator National Heart, Lung & Blood Institute
11:10-11:40am CADASIL Consortium: Past, Present, & Future presented by Michael Geschwind, MD, PhD UCSF Dept. of Neurology
11:40-11:55am CADASIL Community Natural History Study: Progress and Promise presented by Vinita Bahl, cureCADASIL Board Trustee
11:55-12:10pm Engaging Patient & Community Partners to Advance Meaningful Research presented by Jane Gunther, PhD. cureCADASIL Science Officer and Past President
12:10-12:55pm Engaging Patients & Community Partners in Advancing Meaningful Research Open Discussion Panel lead by Jane Gunther PhD., cureCADASIL Science Officer and Past President
12:25-12:30pm Closing Remarks Jane Gunther PhD., cureCADASIL Science Officer and Past President