Research Supported by Us

Since 2020, cureCADASIL has been proud to support groundbreaking CADASIL research studies through Million Dollar Bike Ride grants, which are only possible through your donations and fundraising efforts. Read our list of awardees below.

2026

Awardee: Osama Harraz MSc, Ph.D.,

Title: "Combating Neurovascular Degeneration in CADASIL by Targeting Piezol"

Grant Amount: $80,000

Funding Period: February 1, 2026 – January 31, 2027


2025

Awardee: Michael Wang, M.D., Ph.D., University of Michigan

Title: "Small Molecule Inhibition of NOTCH3 Conformational Alterations"

Grant Amount: $101,776

Funding Period: February 1, 2025 – January 31, 2026


2024

Awardee: Helena Karlström, Karolinska Institutet

Title: "Immunotherapy and Improved Diagnosis and Prognosis of the Small Vessel Disease CADASIL"

Grant Amount: $109,856

Funding Period: February 1, 2024 – January 31, 2025


2023

Awardee: Fabrice Dabertrand, MD, University of Colorado

Title: "Advance in PIP2 Treatment to Restore Capillary Blood Flow"

Grant Amount: $117,734

Funding Period: February 1, 2023 – January 31, 2024


2022

Awardee: Israel Fernández Cadenas, Fundació Privada Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Title: "Single-Nuclei RNA-Seq for CADASIL Understanding and Therapeutic Target Discovery"

Grant Amount: $60,228

Funding Period: February 1, 2022 – January 31, 2023

Awardee: Saskia Lesnik-Oberstein, Leiden University Medical Center

Title: "Modelling CADASIL with Patient iPSC Based 3D Vessel-on-Chip"

Grant Amount: $60,228

Funding Period: February 1, 2022 – January 31, 2023


2021

Awardee: Masayo Koide, University of Vermont Larner College of Medicine

Title: "HB-EGF/EGFR Signaling in Capillary Dysfunction in CADASIL"

Grant Amount: $82,795

Funding Period: February 1, 2021 – January 31, 2022


2020

Awardee: Fabrice Dabertrand, MD, University of Colorado

Title: "Pericyte Contractility in CADASIL"

Grant Amount: $81,951

Funding Period: February 1, 2020 – January 31, 2021