4th Annual cureCADASIL Patient-Investigator Meeting
The Past, Present, and Future come together — June 27, 2026
Thank you to our presenters, attendees, and Board for another strong PIM. The presentations made clear that research efforts are becoming more aligned, that momentum is building across the community, and that patient participation remains central to continuing this progress in research.
We'll be updating this page with recordings and presentation materials so you can go back to the full conversations and hear directly from the speakers and attendees. There's real value in taking the time to listen through how this work is evolving, where the needs are now, and how you can help further this work.
If you have any questions, please contact us at info@curecadasil.org
| Time | Event |
|---|---|
| 9:00–9:10 am | WelcomeBert Kasiske, cureCADASIL 2026 President |
| 9:10–9:40 am | Chan Zuckerberg Initiative Results & Future DirectionsLighwa Ncube, Clinical Research Manager & Nikolas Karvelas, Postdoctoral Fellow, Elahi Lab, Icahn School of Medicine at Mt. Sinai |
| 9:40–10:10 am | Immunization Therapies for CADASILHelena Karlström, Associate Professor & Senior Lecturer, Karolinska Institutet — 2024 MDBR Recipient |
| 10:10–10:40 am | Small Molecule, Big Hopes for CADASIL Therapy Targeting RUNX1Joe Arbolea-Velasquez, MD, PhD, Associate Scientist, Schepens Eye Research Institute, Harvard Medical School |
| 10:40–11:10 am | NIH Program UpdateManfred Boehm, MD, Senior Investigator, National Heart, Lung & Blood Institute |
| 11:10–11:40 am | CADASIL Consortium: Past, Present, & FutureMichael Geschwind, MD, PhD, UCSF Dept. of Neurology |
| 11:40–11:55 am | CADASIL Community Natural History Study: Progress and PromiseVinita Bahl, cureCADASIL Board Trustee |
| 11:55 am–12:10 pm | Engaging Patient & Community Partners to Advance Meaningful ResearchJane Gunther, PhD, cureCADASIL Science Officer and Past President |
| 12:10–12:25 pm | Engaging Patients & Community Partners in Advancing Meaningful Research — Open Discussion PanelLed by Jane Gunther, PhD, cureCADASIL Science Officer and Past President |
| 12:25–12:30 pm | Closing RemarksJane Gunther, PhD, cureCADASIL Science Officer and Past President |
The cureCADASIL Patient-Investigator Meeting is made possible in part by grant 2022-316712 from the Chan Zuckerberg Initiative DAF, an advised fund of the Silicon Valley Community Foundation.
Thank you to the United Leukodystrophy Foundation for their ongoing support of our efforts to connect with the CADASIL community.
The progress shared at this year's PIM is made possible by donors like you. Every gift funds the research that gives hope to families living with CADASIL around the world.
cureCADASIL
PO Box 390023, Edina, MN 55439
info@curecadasil.org